USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: H2BFS_HUMAN

USC-OGP 2-DE database:  H2BFS_HUMAN


General information about the entry
View entry in simple text format
Entry nameH2BFS_HUMAN
Primary accession numberP57053
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Histone H2B type F-S; AltName: Full=Histone H2B.s; Short=H2B/s;.
Gene nameName=H2BFS
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

Homo sapiens (Human)
  map experimental info

pI=4.39; Mw=16914
pI=5.13; Mw=16684

UniProtKB/Swiss-ProtP57053; H2BFS_HUMAN.

2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.

External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameH2BFS_HUMAN
Primary accession numberP57053
Secondary accession number(s) A0AVF9 Q5R2W0
Sequence was last modified on January 23, 2007 (version 2)
Annotations were last modified on March 15, 2017 (version 150)
Name and origin of the protein
DescriptionRecName: Full=Histone H2B type F-S; AltName: Full=Histone H2B.s; Short=H2B/s;
Gene nameName=H2BFS
Encoded onName=H2BFS
KeywordsAcetylation; Antibiotic; Antimicrobial; Chromosome; Complete proteome; Direct protein sequencing; DNA-binding; Glycoprotein; Isopeptide bond; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation.
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
EMBLAB041017; BAD74065.1; -; Genomic_DNA
EMBLAP001751; BAA95538.1; -; Genomic_DNA
PIRS65409; S65409; .
RefSeqXP_006723981.1; XM_006723918.3; .
ProteinModelPortalP57053; -; .
SMRP57053; -; .
IntActP57053; 7; .
MINTMINT-5000257; -; .
STRING9606.ENSP00000349430; -; .
iPTMnetP57053; -; .
PhosphoSitePlusP57053; -; .
SwissPalmP57053; -; .
DMDM9973351; -; .
EPDP57053; -; .
MaxQBP57053; -; .
PaxDbP57053; -; .
PeptideAtlasP57053; -; .
PRIDEP57053; -; .
TopDownProteomicsP57053; -; .
EnsemblENST00000599962; ENSP00000481622; ENSG00000234289; .
GeneID102724334; -; .
KEGGhsa:102724334; -; .
UCSCuc002zdj.2; human; .
DisGeNET102724334; -; .
DisGeNET54145; -; .
GeneCardsH2BFS; -; .
H-InvDBHIX0040944; -; .
HPAHPA042205; -; .
HPAHPA043013; -; .
HPAHPA048671; -; .
neXtProtNX_P57053; -; .
OpenTargetsENSG00000234289; -; .
eggNOGKOG1744; Eukaryota; .
eggNOGENOG4111NV5; LUCA; .
GeneTreeENSGT00870000136414; -; .
HOVERGENHBG007774; -; .
InParanoidP57053; -; .
OrthoDBEOG091G0XGD; -; .
ReactomeR-HSA-1221632; Meiotic synapsis; .
ReactomeR-HSA-171306; Packaging Of Telomere Ends; .
ReactomeR-HSA-201722; Formation of the beta-catenin:TCF transactivating complex; .
ReactomeR-HSA-212300; PRC2 methylates histones and DNA; .
ReactomeR-HSA-2299718; Condensation of Prophase Chromosomes; .
ReactomeR-HSA-2559580; Oxidative Stress Induced Senescence; .
ReactomeR-HSA-2559582; Senescence-Associated Secretory Phenotype (SASP); .
ReactomeR-HSA-2559586; DNA Damage/Telomere Stress Induced Senescence; .
ReactomeR-HSA-427359; SIRT1 negatively regulates rRNA Expression; .
ReactomeR-HSA-427389; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; .
ReactomeR-HSA-427413; NoRC negatively regulates rRNA expression; .
ReactomeR-HSA-5250924; B-WICH complex positively regulates rRNA expression; .
ReactomeR-HSA-5334118; DNA methylation; .
ReactomeR-HSA-5578749; Transcriptional regulation by small RNAs; .
ReactomeR-HSA-5617472; Activation of anterior HOX genes in hindbrain development during early embryogenesis; .
ReactomeR-HSA-5625886; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; .
ReactomeR-HSA-5693565; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; .
ReactomeR-HSA-5693571; Nonhomologous End-Joining (NHEJ); .
ReactomeR-HSA-5693607; Processing of DNA double-strand break ends; .
ReactomeR-HSA-606279; Deposition of new CENPA-containing nucleosomes at the centromere; .
ReactomeR-HSA-69473; G2/M DNA damage checkpoint; .
ReactomeR-HSA-73728; RNA Polymerase I Promoter Opening; .
ReactomeR-HSA-73777; RNA Polymerase I Chain Elongation; .
ReactomeR-HSA-912446; Meiotic recombination; .
ReactomeR-HSA-977225; Amyloid fiber formation; .
PROPR:P57053; -; .
ProteomesUP000005640; Chromosome 21; .
GenevisibleP57053; HS; .
GOGO:0005829; C:cytosol; IDA:HPA; .
GOGO:0005615; C:extracellular space; IDA:UniProtKB; .
GOGO:0005654; C:nucleoplasm; IDA:HPA; .
GOGO:0000786; C:nucleosome; IEA:UniProtKB-KW; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:0003677; F:DNA binding; IBA:GO_Central; .
GOGO:0019731; P:antibacterial humoral response; IDA:UniProtKB; .
GOGO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB; .
GOGO:0002227; P:innate immune response in mucosa; IDA:UniProtKB; .
GOGO:0006334; P:nucleosome assembly; IBA:GO_Central; .
GOGO:0021762; P:substantia nigra development; IEP:UniProtKB; .
Gene3D1.10.20.10; -; 1; .
InterProIPR009072; Histone-fold; .
InterProIPR007125; Histone_H2A/H2B/H3; .
InterProIPR000558; Histone_H2B; .
PANTHERPTHR23428; PTHR23428; 1; .
PfamPF00125; Histone; 1; .
SMARTSM00427; H2B; 1; .
SUPFAMSSF47113; SSF47113; 1; .

USC-OGP 2-DE database image

Gateways to other related servers

Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server